Opie and Anthony's April Fools Day Prankon Mayor Menino of Boston. For their annual April Fools prank, Opie called a severely hung over Anthony bright and early with the idea "Let's tell all of Boston that Mayor Menino died in a fiery car crash!". Anthony agreed. The fallout from this prank was far greater than anyone had anticipated. It gained citywide attention and news coverage, and was made worse by the fact that Mayor Menino could not be reached at the time because he was in the air on his way back from Florida. April 2-Opie and Anthony's last live show on WAAF. April 9-Opie and Anthony are fired. The bbboys are signed to legendary New York rock station 102.7 WNEW. Over the next year, they were locked in battle with the other DJs, due to their interjection of humor between songs. "Shut up and play the music" was heard all too often. June 26-Opie and Anthony's first show on WNEW.
WNEW drops the Rock format altogether, and focuses soley on "Hot Talk". Opie and Anthony get their afternoon-drive talk radio slot, and O&A version 2.0 begins. WNEW flips to "FM Talk @ 102.7".
O&A hit Number 1 in the NY market afternoon drive slot. As the show gains rampant popularity, more and more comedians appear on and become friends of the show. Jim Norton becomes a regular after several guest appearances with Andrew Dice Clay. The Voyeur Bus makes headlines, as Mayor Rudy Giuliani calls for the arrest of all those aboard the glass-walled bus, including Jimmy and Lewis Black.
Opie and Anthony's contract is up for renewal, but no one at Infinity Broadcasting is sure how to proceed. On one hand, there is major controversy surrounding some of the radio bits and promotions, like Sex for Sam, the 55 Gallon Drum Challenge, and the Homeless Shopping Spree, but on the other hand, the outstanding ratings and the duo's confidence in their show suggested that the next logical step would have to be syndication. June 11- After taking a 2 week break while their contract was in limbo, Opie and Anthony returned to the airwaves, now syndicated to 94.1 WYSP in Philadelphia. Over the next 6 months, syndication was expanded to 18 additional markets, including WJFK in Washington, DC, and WBCN in Boston. August- Opie and Anthony return to the Boston airwaves, syndicated on WBCN, the rival station of their former home, WAAF. September 11- The 9/11 terrorist attacks. O&A broadcast outside of Manhattan because of the chaos in the city. In the weeks following the attack, O&A show another side of themselves as they take calls from people affected by the attacks. December 11- Homeless Shopping Spree 2001.
March of 2002 Anthony and Jennifer officially settle their divorce. May 9 - The Dead Monkey Hummer at WYSP. May 14 - The infamous Eddie the Murderer calls in. May 17 - O&A play tracks from Eminem's upcoming album The Eminem Show without permission. August 15 - During the Third Annual Sex for Sam competition, a couple (Brian Florence and Loretta Harper) was allegedly caught having "Pew-Rocking Sex" in Saint Patrick's Cathedral. Both of the contestants, as well as their spotter, Paul Mercurio were arrested and taken downtown. Opie and Anthony both knew immediately that this was the big one, and they would most likely be out of jobs. August 16 - Opie and Anthony go on live, alas for the last time. Neither of the bbboys were allowed to speak of the incident, referring to it only as the Peanut Butter and Jelly incident. The first thing broadcast over the air that day was Opie uttering the words "We're F-'ed". The last words were "Your Mom's Box". August 22 - Infinity Broadcasting made the announcement that The Opie and Anthony Show had been cancelled. However, they had not been fired. Infinity continued to pay out the remaining two years of their contract. O&A were not allowed to work elsewhere until the contract expired.